GDNF wt Allele

Human GDNF wild-type allele is located within 5p13.1-p12 and is approximately 24 kb in length. This allele, which encodes glial cell line-derived neurotrophic factor protein, is involved in both the survival and differentiation of dopaminergic neurons and in apoptotic motor neuron protection induced by axotomy. Mutantions in the gene produce variant alleles that are associated with Hirschsprung disease. (NCI Thesaurus)

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GDNF Gene

This gene is involved in neurogenesis. It plays a role in promoting the differential and survival of neurons.

GDNF Family Receptor Alpha-2

GDNF family receptor alpha-2 protein (464 aa, 52 kD) is a cell communication process protein that is encoded by the human GFRA2…

GDF9 wt Allele

Human GDF9 wild-type allele is located in the vicinity of 5q31.1 and is approximately 3 kb in length. This allele, which encodes…

GDF9 Gene

This gene plays a role in ovarian folliculogenesis and normal ovulation.

GDF5 wt Allele

Human GDF5 wild-type allele is located in the vicinity of 20q11.2 and is approximately 5 kb in length. This allele, which encodes…

GDF5 Gene

This gene is involved in the regulation of axial bone growth during development and plays a role in cellular differentiation.