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GEM 231
Definition 1
A drug that may inhibit the growth of malignant tumors. (NCI Dictionary)
Definition 2
A mixed backbone oligonucleotide exhibiting antitumor activity. GEM-231 is complementary to the RI alpha subunit of Protein Kinase A (PKA), resulting in downregulation of PKA expression and ultimately tumor growth. (NCI Thesaurus)
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