Health / Medical Topics

    Gene Rearrangement

    Any DNA sequence rearrangement that results in the creation of a novel protein-coding capacity. Within certain genes, gene rearrangement is a normal part of development, facilitating the affinity maturation of B and T lymphocytes as well as class switching of immunoglobulins. (NCI Thesaurus)




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    A variation in the amino acid sequence of a specific gene product.
    A protein, RNA or a complex that contains proteins and/or RNA.
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    The result of any gain, loss or alteration of the sequences comprising a gene, including all sequences transcribed into RNA.

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