| Library / English Dictionary |
GHRELIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A gastrointestinal hormone produced by epithelial cells lining the fundus of the stomach; appears to be a stimulant for appetite and feeding, but is also a strong stimulant of growth hormone secretion from the anterior pituitary
Classified under:
Hypernyms ("ghrelin" is a kind of...):
gastrointestinal hormone; GI hormones (hormones that affect gastrointestinal functioning)
Context examples:
Up until now, scientists knew that leptin — a hormone released by fatty tissue, reduces appetite, while ghrelin — a hormone released by stomach tissue makes us want to eat more.
(New Appetite Control Mechanism Found in Brain, The Titi Tudorancea Bulletin)
Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland.
(Ipamorelin, NCI Thesaurus)
Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of ghrelin.
(Anamorelin, NCI Thesaurus)
An orally available synthetic mimetic of the growth hormone (GH) secretagogue ghrelin with potential anti-cachexia activity.
(Macimorelin, NCI Thesaurus)
A ghrelin peptide analogue with potential anti-cachexia activity.
(Ghrelin Peptide Analogue, NCI Thesaurus)
Upon oral administration, macimorelin mimics endogenous ghrelin by stimulating appetite and binds to the growth hormone secretagogue receptor GHSR in the central nervous system, thereby mimicking the GH-releasing effects of ghrelin from the pituitary gland.
(Macimorelin, NCI Thesaurus)
Upon subcutaneous administration, ghrelin peptide analogue binds to and stimulates the G protein-coupled growth hormone secretagogue receptor (GHSR) in the central nervous system (CNS), thereby mimicking the appetite-stimulating and growth hormone-releasing effects of endogenous ghrelin.
(Ghrelin Peptide Analogue, NCI Thesaurus)
