| Health / Medical Topics |
Giant Cell Tumor of Bone
Definition 1
A benign or malignant bone tumor, usually arising in the end of long bones or the vertebrae. The tumor is composed of round or oval mononuclear cells and uniformly distributed osteoclast-like giant cells. Clinical presentation includes pain, edema, and decreased range of motion in the affected joint. (NCI Thesaurus)
Definition 2
A neoplasm of bone comprised of osteoclast-like giant cells and mononuclear cells, for which the malignancy status has not been established. (NCI Thesaurus/CDISC)
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