Gitelman Syndrome

An inherited disorder caused by mutations in the SLC12A3 gene. It is characterized by deficient reabsorption of electrolytes in the distal convoluted tubules of the kidneys. It results in hypochloremic metabolic alkalosis, hypokalemia, hypocalciuria, and hypomagnesemia. (NCI Thesaurus)

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GIT2 wt Allele

Human GIT2 wild-type allele is located in the vicinity of 12q24.1 and is approximately 66 kb in length. This allele, which encodes…

GIT2 Gene

This gene is involved in signal transduction and regulation of receptor signaling.

GIT1 wt Allele

Human GIT1 wild-type allele is located in the vicinity of 17p11.2 and is approximately 16 kb in length. This allele, which encodes…

GIT1 Gene

This gene plays a role in signal transduction and cytoskeletal remodeling.

GISTIC

A statistical approach for identifying genomic regions of aberration that are more likely to drive cancer pathogenesis. The method identifies those regions…

GIST

A type of tumor that usually begins in cells in the wall of the gastrointestinal tract. It can be benign or…