| Health / Medical Topics |
Glisoxepide
A second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, glisoxepide exerts greater binding affinity than the first-generation compounds. Glisoxepide shows peroxisome proliferator-activated receptor (PPAR) gamma agonistic activity, has a short half-life and is excreted in both the bile and urine. (NCI Thesaurus)
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Human GLIS2 wild-type allele is located in the vicinity of 16p13.3 and is approximately 25 kb in length. This allele, which encodes…
This gene is involved in transcriptional regulation and signaling pathway modulation.
