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GLUCAGON
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A hormone secreted by the pancreas; stimulates increases in blood sugar levels in the blood (thus opposing the action of insulin)
Classified under:
Hypernyms ("glucagon" is a kind of...):
endocrine; hormone; internal secretion (the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect)
Context examples:
When glucose levels are low during long periods between meals the enzyme glucagon secreted by the pancreas stimulates adipose lipase activity to release fatty acids from triglycerides.
(Beta-Oxidation of Fatty Acids Pathway, NCI Thesaurus/BIOCARTA)
Although insulin and glucagon play important roles in regulating the response of cells to nutrients, cells also respond to carbohydrates through transcriptional regulation by the glucose responsive transcription factor ChREBP.
(ChREBP Pathway, NCI Thesaurus/BIOCARTA)
A cell in the periphery of the pancreatic islets that secretes glucagon.
(Alpha Cell, NCI Thesaurus)
This allele, which encodes glucagon protein, is involved in the stimulation of glycogen processing, gluconeogenesis and the absorption of nutrients by the gut.
(GCG wt Allele, NCI Thesaurus)
The alpha cells make glucagon, which raises the level of glucose in the blood; the beta cells make insulin; the delta cells make somatostatin.
(Pancreas, NCI Thesaurus)
By mimicking amylin, davalintide, which has a half-life similar to amylin, slows gastric emptying, inhibits digestive secretions (gastric acid, pancreatic enzymes, and bile), reduces glucagon secretion, and increases satiety.
(Davalintide, NCI Thesaurus)
This prolongs incretin activity, increases postprandial insulin release, decreases glucagon release, delays gastric emptying and lowers blood glucose levels.
(Dipeptidyl Peptidase-4 Inhibitor, NCI Thesaurus)
A pancreatic cell that produces hormones (e.g., insulin and glucagon) that are secreted into the bloodstream.
(Endocrine pancreas cell, NCI Dictionary)
An endocrine neoplasm producing glucagon.
(Enteroglucagonoma, NCI Thesaurus)
This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited.
(Alfentanil, NCI Thesaurus)
