Health / Medical Topics

    Glycoprotein IIb/IIIa Antagonist

    A class of agents that act by selectively inhibiting glycoprotein IIb/IIIa with anticoagulant activity. Glycoprotein IIb/IIIa antagonists bind to and block the activation of the platelet-surface integrin glycoprotein IIb/IIIa, thus preventing the binding of fibrinogen and von Willebrand factor leading to the inhibition of platelet activation and aggregation. (NCI Thesaurus)




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