Health / Medical Topics

    gp100 Antigen

    Definition 1

    A melanoma-associated antigen. When administered in a vaccine formulation, gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune response against tumors that express this antigen, which may result in a reduction in tumor size. (NCI Thesaurus)

    Definition 2

    A tumor-specific antigen used in the development of cancer vaccines. (NCI Dictionary)




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