Health / Medical Topics |
GPNMB wt Allele
Human GPNMB wild-type allele is located in the vicinity of 7p15 and is approximately 39 kb in length. This allele, which encodes transmembrane glycoprotein NMB, may be involved in the modulation of cell proliferation. Aberrant expression of the gene is associated with glioblastoma multiforme and other neoplasms. (NCI Thesaurus)
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