Library / English Dictionary

    GRANULOMA

    Pronunciation (US): Play  (GB): Play

    Irregular inflected form: granulomata  Listen to US pronunciation  Listen to GB pronunciation

     I. (noun) 

    Sense 1

    Meaning:

    A tumor composed of granulation tissue resulting from injury or inflammation or infectionplay

    Classified under:

    Nouns denoting stable states of affairs

    Hypernyms ("granuloma" is a kind of...):

    neoplasm; tumor; tumour (an abnormal new mass of tissue that serves no purpose)

    Hyponyms (each of the following is a kind of "granuloma"):

    gumma (a small rubbery granuloma that is characteristic of an advanced stage of syphilis)

    Derivation:

    granulomatous (relating to or characterized by granulomas)

    Credits

     Context examples: 

    Certain allelic variants of the G6PD gene cause G6PD protein deficiency which, in turn, is associated with acute hemolysis, chronic granuloma, neonatal jaundice, and severe non-spherocytic hemolytic anemia.

    (G6PD wt Allele, NCI Thesaurus)

    An autoimmune necrotizing vasculitis with the formation of granulomas.

    (Churg-Strauss Syndrome, NCI Thesaurus)

    Formation of non-necrotizing granulomas in the skin.

    (Cutaneous Sarcoidosis, NCI Thesaurus)

    It is most commonly caused by trichophyton rubrum and is characterized by the formation of spongy granulomas which persist for three to four months and leaves deep scars.

    (Deep Seated Dermatophytosis, NCI Thesaurus)

    Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease.

    (Langerhans cell histiocytosis, NCI Thesaurus/WHO)

    A recessive X-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation.

    (Chronic Granulomatous Disease, NLM, Medical Subject Headings)

    A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis.

    (Crohn disease, NCI Thesaurus)

    Morphologically, eosinophilic granuloma is characterised by the presence of Langerhans cells in a characteristic milieu which includes histiocytes, eosinophiles neutrophiles, and small, mature lymphocytes.

    (Eosinophilic Granuloma, NCI Thesaurus)

    There are no granulomas present.

    (Non Specific Chronic Endometritis, NCI Thesaurus)

    Widespread necrotizing angiitis with granulomas.

    (Churg-Strauss Syndrome, NLM, Medical Subject Headings)


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