GRB7 wt Allele

Human GRB7 wild-type allele is located in the vicinity of 17q12 and is approximately 9 kb in length. This allele, which encodes growth factor receptor-bound protein 7, is involved in the regulation of both epidermal growth factor receptor and ephrin receptor signal transduction pathways and plays a role in the modulation of both cellular adhesion and migration. (NCI Thesaurus)

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GRB7 Gene

This gene is involved in signal transduction and protein binding.

GRB2-Related Adaptor Protein

This protein is a member of the GRB2/Sem5/Drk family. It functions as a cytoplasmic signaling protein which contains an SH2 domain flanked…

GRB2-Associated-Binding Protein 1

GRB2-associated-binding protein 1 (694 aa, ~77 kDa) is encoded by the human GAB1 gene. This protein is involved in intracellular signaling from…

GRB2-Associated Binding Protein 2

GRB2-Associated Binding Protein 2 (GAB2), encoded by the human GAB2 gene, is the principal activator of phosphatidylinositol-3 kinase in response to activation…

GRB2 wt Allele

Human GRB2 wild-type allele is located within 17q24-q25 and is approximately 88 kb in length. This allele, which encodes growth factor receptor-bound…

GRB2 Protein

An adaptor protein which bridges cell surface tyrosine kinase receptors with downstream signal transmitters such as ras p21. (from IRB Summaries) …