Health / Medical Topics |
GTF2H5 wt Allele
Human GTF2H5 wild-type allele is located in the vicinity of 6q25.3 and is approximately 22 kb in length. This allele, which encodes general transcription factor IIH subunit 5 protein, plays a role in the regulation of both RNA polymerase II-mediated transcription and nucleotide excision repair. Mutation of the gene is associated with trichothiodystrophy, complementation group A. (NCI Thesaurus)
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This gene is involved in the regulation of both RNA polymerase II-mediated transcription and nucleotide excision repair.
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