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    GUINEA PIG

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Stout-bodied nearly tailless domesticated cavy; often kept as a pet and widely used in researchplay

    Synonyms:

    Cavia cobaya; guinea pig

    Classified under:

    Nouns denoting animals

    Hypernyms ("guinea pig" is a kind of...):

    cavy (short-tailed rough-haired South American rodent)

    Sense 2

    Meaning:

    A person who is subjected to experimental or other observational procedures; someone who is an object of investigationplay

    Example:

    the cases that we studied were drawn from two different communities

    Synonyms:

    case; guinea pig; subject

    Classified under:

    Nouns denoting people

    Hypernyms ("guinea pig" is a kind of...):

    individual; mortal; person; somebody; someone; soul (a human being)

    Credits

     Context examples: 

    The domesticated guinea pig, Cavia porcellus.

    (Guinea Pig, NCI Thesaurus)

    Finally, I will assuredly give some account of the toxodon, the giant ten-foot guinea pig, with projecting chisel teeth, which we killed as it drank in the gray of the morning by the side of the lake.

    (The Lost World, by Sir Arthur Conan Doyle)

    Genetic loci in the vertebrate major histocompatibility complex which encode polymorphic characteristics not related to immune responsiveness or complement activity, e.g., B loci (chicken), DLA (dog), GPLA (guinea pig), H-2 (mouse), RT-1 (rat), HLA-A, -B, and -C class I genes of man.

    (MHC Class I Gene, NCI Thesaurus)

    This protein is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix.

    (Acrosin Binding Protein, NCI Thesaurus/LocusLink)

    Encoded by human ACRBP Gene, 540-amino acid 61 kD Acrosin Binding Protein (CT Family) is similar to proacrosin binding protein sp32 precursor found in pig, mouse, and guinea pig. Expressed in normal testis only, but detected in a range of tumor types such as bladder, breast, lung, liver, and colon, this immunogenic protein is located in the sperm acrosome and may package and condense proacrosin in the acrosomal matrix.

    (Acrosin Binding Protein, NCI Thesaurus)

    Glutamine supplements can suppress reactivation of herpes simplex virus (HSV) in mice and guinea pigs.

    (Glutamine suppresses herpes in mice and guinea pigs, National Institutes of Health)

    The Dunkin Hartley guinea pig is a crepuscular mammalian herbivore that is tailless with short legs and a large head.

    (Dunkin Hartley Guinea Pig, NCI Thesaurus)

    The Hartley guinea pig was imported from the Medical Research Council, Millhill, England, to Charles River in 1968 for propagation.

    (Hartley Guinea Pig, NCI Thesaurus)

    According to a study, companion animals — like dogs, cats or the guinea pigs — may prove to be a helpful addition to treatment programs designed to help children with ASDs improve their social skills and interactions with other people.

    (Animals’ presence may ease social anxiety in kids with autism, NIH)

    Although several chemical mediators are active upon eosinophils in vitro, a central role in eosinophil accumulation in vivo is emerging for the C-C chemokine eotaxin, which was first identified in a guinea pig model of allergic airway inflammation using protein purification and microsequencing.

    (Allergy Chemokine Network Pathway, NCI Thesaurus/BIOCARTA)


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