Health / Medical Topics

    H19 Imprinted Maternal Untranslated mRNA

    Maternally expressed exclusively and developmentally regulated human putative tumor suppressor H19 Gene encodes H19 Imprinted Maternal Untranslated mRNA. Expression in developing skeletal and smooth muscles correlates with specific differentiation events. It accumulates during skeletal muscle development with maximal adult expression and correlates with the nonproliferative, actin-positive muscle cell phenotype. Loss of H19 expression may be involved in Wilms tumorigenesis. (NCI Thesaurus)




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