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HALLMARK
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A distinctive characteristic or attribute
Synonyms:
earmark; hallmark; stylemark; trademark
Classified under:
Nouns denoting attributes of people and objects
Hypernyms ("hallmark" is a kind of...):
characteristic (a distinguishing quality)
Hyponyms (each of the following is a kind of "hallmark"):
mold; mould (a distinctive nature, character, or type)
Sense 2
Meaning:
A mark on an article of trade to indicate its origin and authenticity
Synonyms:
assay-mark; authentication; hallmark
Classified under:
Nouns denoting communicative processes and contents
Hypernyms ("hallmark" is a kind of...):
mark; marker; marking (a distinguishing symbol)
II. (verb)
Sense 1
Present simple (first person singular and plural, second person singular and plural, third person plural) of the verb hallmark
Context examples:
One of the major hallmarks of Alzheimer’s disease is amyloid plaques that are found in between nerve cells.
(Alzheimer’s protein may have natural antibiotic role, NIH)
That prompted them to create a first-of-its-kind platform mimicking hallmarks of early porcine CAVD in a lab dish.
(New Hope for Stopping An Understudied Heart Disease in Its Tracks, The Titi Tudorancea Bulletin)
But the amount of tau tangles, another hallmark of the disease, and the one more correlated with how thinking and memory are affected, was relatively low.
(Unique case of disease resistance reveals possible Alzheimer’s treatment, National Institutes of Health)
The hallmark of EPEC/EHEC infections is induction of attaching and effacing (A/E) lesions that damage intestinal epithelial cells.
(Pathogenic Escherichia coli Infection Pathway, NCI Thesaurus/KEGG)
But the identification in the aged chimpanzees of amyloid beta and tau lesions, hallmarks of Alzheimer's diagnosis, is a significant advance in understanding the brain and Alzheimer's.
(New research detects Alzheimer's disease markers in nonhuman primates, National Science Foundation)
A hallmark of CD183 is its prominent expression in in vitro cultured effector/memory T cells, and in T cells present in many types of inflamed tissues.
(Chemokine (C-X-C Motif) Receptor 3, NCI Thesaurus/LocusLink)
When the researchers looked at the affected brain cells more closely, they saw the buildup of a protein called α-synuclein, a hallmark of Parkinson’s, and defects in pathways that clear cellular garbage.
(Scientists find a role for Parkinson’s gene in the brain, The Titi Tudorancea Bulletin)
Perforin proteins form pores in the membranes of the attacked cell, allowing the entry of Granzyme A and Granzyme B. Granzyme B induces caspase activation and cleavage of factors like ICAD, releasing DFF40 to fragment DNA, one of the hallmarks of apoptotic cell death.
(Granzyme A Mediated Apoptosis Pathway, NCI Thesaurus/BIOCARTA)
In studies using human cells and animals models, the researchers found that the medication, called amphotericin, helps lung cells function in a way that could make it easier for patients to fight chronic bacterial lung infections that are a hallmark of the disease.
(Scientists find new approach that shows promise for treating cystic fibrosis, National Institutes of Health)
But now, using a novel planet-hunting technique that identifies unusual patterns in the flow of gas within a planet-forming disc around a young star, two teams of astronomers have each confirmed distinct, telltale hallmarks of newly formed planets orbiting an infant star.
(ALMA Discovers Trio of Infant Planets around Newborn Star, ESO)
