HDAC2 wt Allele

Human HDAC2 wild-type allele is located within 6q21 and is approximately 30 kb in length. This allele, which encodes histone deacetylase 2 protein, is involved in both the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4) and the formation of transcriptional repressor complexes. Reduced expression of the HDAC2 gene is associated with chronic obstructive pulmonary disease. (NCI Thesaurus)

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HDAC2 Gene

This gene is involved in chromatin remodeling, repression of gene expression and control of both cell proliferation and differentiation.

HDAC11 wt Allele

Human HDAC11 wild-type allele is located in the vicinity of 3p25.1 and is approximately 27 kb in length. This allele, which encodes…

HDAC11 Gene

This gene is involved in deacetylation of histones.

HDAC10 wt Allele

Human HDAC10 wild-type allele is located in the vicinity of 22q13.31 and is approximately 6 kb in length. This allele, which encodes…

HDAC10 Gene

This gene plays a role in the regulation of histone acetylation.

HDAC1 wt Allele

Human HDAC1 wild-type allele is located within 1p34 and is approximately 42 kb in length. This allele, which encodes histone deacetylase 1…