HDAC3 wt Allele

Human HDAC3 wild-type allele is located within 5q31 and is approximately 16 kb in length. This allele, which encodes histone deacetylase 3 protein, plays a role in the both the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4) and the binding of transcription factor YY1. Deregulation of HDAC3 gene expression is associated with colon cancer. (NCI Thesaurus)

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HDAC3 Gene

This gene plays a role in chromatin remodeling, repression of gene expression and modulation of both cell growth and apoptosis.

HDAC2 wt Allele

Human HDAC2 wild-type allele is located within 6q21 and is approximately 30 kb in length. This allele, which encodes histone deacetylase 2…

HDAC2 Gene

This gene is involved in chromatin remodeling, repression of gene expression and control of both cell proliferation and differentiation.

HDAC11 wt Allele

Human HDAC11 wild-type allele is located in the vicinity of 3p25.1 and is approximately 27 kb in length. This allele, which encodes…

HDAC11 Gene

This gene is involved in deacetylation of histones.

HDAC10 wt Allele

Human HDAC10 wild-type allele is located in the vicinity of 22q13.31 and is approximately 6 kb in length. This allele, which encodes…