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HELICAL
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I. (adjective)
Sense 1
Meaning:
In the shape of a coil
Synonyms:
coiling; helical; spiral; spiraling; turbinate; volute; voluted; whorled
Classified under:
Similar:
coiled (curled or wound (especially in concentric rings or spirals))
Derivation:
helix (a structure consisting of something wound in a continuous series of loops)
Context examples:
Bisantrene intercalates with and disrupts the helical structure of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication.
(Bisantrene Hydrochloride, NCI Thesaurus)
The alpha-helical BH3 domain (9 amino acids) represents a minimal death domain and is essential for the activity of pro-apoptotic members of the bcl-2 family.
(BH3 Domain, NCI Thesaurus)
Conversion of p35 to p25 causes prolonged activation and mislocalization of cdk5 and the hyperphosphorylates tau, leading to the formation of paired helical filaments and promotion of apoptosis.
(Alzheimer's Disease Pathway BioCarta, NCI Thesaurus/BIOCARTA)
A shape distortion in the z-axis resulting from the weighting function used in the helical interpolation algorithm.
(Helical Interpolation Artifact, NCI Thesaurus)
This polypeptide is comprised of the amino terminal portions of fibrillar collagen, which are not part of the triple helical structure.
(N-Telopeptide, NCI Thesaurus)
A genus of gram-negative helical, curved, or straight microaerophilic bacteria with rounded ends and multiple sheathed flagella (unipolar or bipolar and lateral) with terminal bulbs.
(Helicobacter, NCI Thesaurus)
A family of filamentous viruses with helical capsids and glycoprotein projections on their surface.
(Filoviridae, NCI Thesaurus)
Alpha helical hydrophilic LBC is conserved among vertebrates and expressed in skeletal muscle, heart, lung, and hematopoietic cells.
(A Kinase Anchor Protein 13, NCI Thesaurus)
Drug-, radiation-induced, or spontaneous injuries to DNA that introduce deviations from its normal double-helical conformation.
(DNA Damage, NCI Thesaurus)
This type of domain consists of a twelve residue loop flanked on both side by a twelve residue alpha-helical domain.
(Calcium-Binding Domain, NCI Thesaurus)
