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Hemidesmosome
Definition 1
Half desmosomes that occur on the basal surface of the stratum basalis of stratified squamous epithelium. (NCI Thesaurus)
Definition 2
An anchoring junction of the cell to a non-cellular substrate, similar in morphology to halves of DESMOSOMES. They are composed of specialized areas of the plasma membrane where INTERMEDIATE FILAMENTS bind on the cytoplasmic face to the transmembrane linkers, INTEGRINS, via intracellular attachment proteins, while the extracellular domain of the integrins binds to EXTRACELLULAR MATRIX PROTEINS. (NLM, Medical Subject Headings)
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