| Health / Medical Topics |
High Grade Mouse MIN
A focal atypical, non-invasive epithelial lesion with severe atypia and high malignant potential. Focal increase of epithelium that contains cells with highly atypical nuclei. Nuclear atypia corresponds to a nuclear score of 2 or three in the Elston-Ellis grading system. These lesions have more severe atypia, higher mitotic rate. Biological criteria is based on transplantation. High risk lesions grow in the gland cleared mammary fat pad and frequently result in tumors and metastasis. (NCI Thesaurus/MMHCC)
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