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High Mobility Group Protein HMG-I
Definition 1
High mobility group protein HMG-I (107 aa, ~12 kDa) is encoded by the human HMGA1 gene. This protein plays a role in the regulation of both transcription and chromatin structure. (NCI Thesaurus)
Definition 2
A protein that binds to the DNA and certain proteins in chromosomes. It is involved in many functions in the cell, and helps protect cells from dying. HMGA1 is found at high levels in several types of cancer cells. (NCI Dictionary)
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