Health / Medical Topics |
HLA-B44-Restricted MAGE-3 Peptide
A peptide comprised of the synthetic human leukocyte antigen (HLA)-B44-binding peptides derived from amino acid sequences of MAGE-3 with potential antitumor activity. Vaccination with HLA-B44-restricted MAGE-3 peptide may elicit a cytotoxic T lymphocyte immune response against tumor cells expressing MAGE-3. MAGE-3 is an antigen found on many tumor cell types, including melanoma and lung, prostate, colon, thyroid, and breast cancers. (NCI Thesaurus)
YOU MAY ALSO LIKE
The determination of the amount of HLA-B27 antigen present in a sample.
HLA-B wild-type allele is located in the vicinity of 6p21.3 and is approximately 3 kb in length. This allele, which encodes HLA…
This gene plays a role in both immune responses and histocompatibility processes.
A peptide vaccine comprised of synthetic HLA-A2- and HLA-A3-binding peptides, derived from amino acid sequences of fibroblast growth factor-5 (FGF-5), combined with…
A synthetic peptide cancer vaccine consisting of HLA-A2-restricted peptides derived from glioma-associated antigens (GAA) with potential immunostimulating and antineoplastic activities. Upon administration,…
A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A2-restricted melanoma-associated antigen peptides tyrosinase (TYR), MART-1(melanoma…