HMGA2 wt Allele

Human HMGA2 wild-type allele is located within 12q15 and is approximately 142 kb in length. This allele, which encodes high mobility group protein HMGI-C, plays a role in chromatin remodeling and DNA-dependent transcriptional regulation. The HMGA2 gene is overexpressed in several types of cancer such as neuroblastomas and pituitary adenomas. Translocation of this gene is associated with lipomas, pulmonary chondroid hamartomas and uterine leiomyomata. (NCI Thesaurus)

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HMGA2 Gene

This gene is involved in chromatin organization and regulation of gene transcription. It also plays a role in development.

HMGA1 wt Allele

Human HMGA1 wild-type allele is located within 6p21 and is approximately 9 kb in length. This allele, which encodes high mobility group…

HMGA1 Gene

This gene plays a role in a number of cellular processes including apoptosis, chromatin organization and transcriptional regulation.

HMGA1

A protein that binds to the DNA and certain proteins in chromosomes. It is involved in many functions in the cell, and…

HMGA Family Protein

Members of this family of high mobility group (HMG) proteins participate in a wide variety of nuclear processes ranging from chromosome and…

HMGA Family Gene

Human HMGA Family Genes encode HMGA proteins that participate in many nuclear processes ranging from chromosome and chromatin mechanics to transcription factors…