Health / Medical Topics |
HNF1alpha-Inactivated Hepatocellular Adenoma
A hepatocellular adenoma caused by inactivating mutations of the HNF1A gene. It is characterized by the presence of lobulated contours, steatosis, and absence of inflammation or nuclear atypia. (NCI Thesaurus)
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A molecular genetic abnormality indicating the presence of inactivating mutation of the HNF1A (hepatocyte nuclear factor 1-alpha) gene.
This gene plays a role in both DNA binding and transcriptional modulation.
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