HNPCC

An inherited disorder in which affected individuals have a higher-than-normal chance of developing colorectal cancer and certain other types of cancer, often before the age of 50. Also called hereditary nonpolyposis colon cancer and Lynch syndrome. (NCI Dictionary)

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HNF1B wt Allele

Human HNF1B wild-type allele is located within 17cen-q21.3 and is approximately 59 kb in length. This allele, which encodes hepatocyte nuclear factor…

HNF1B Gene

This gene is involved in the regulation of transcription.

HNF1alpha-Inactivated Hepatocellular Adenoma

A hepatocellular adenoma caused by inactivating mutations of the HNF1A gene. It is characterized by the presence of lobulated contours, steatosis,…

HNF1A wt Allele

Human HNF1A wild-type allele is located in the vicinity of 12q22-qter; 12q24.2 and is approximately 25 kb in length. This allele, which…

HNF1A Gene Mutation

A molecular genetic abnormality indicating the presence of inactivating mutation of the HNF1A (hepatocyte nuclear factor 1-alpha) gene.

HNF1A Gene

This gene plays a role in both DNA binding and transcriptional modulation.