| Health / Medical Topics |
hTERT I540/R572Y/D988Y Multipeptide Vaccine
A peptide vaccine consisting of multiple epitopes derived from the human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, with potential immunostimulating and antineoplastic activities. hTERT I540/R572Y/D988Y multipeptide vaccine contains strongly antigenic peptide epitopes I540 (9-mer), R572Y (9-mer) and D988Y (10-mer). Vaccination with this agent may elicit a cytotoxic T cell (CTL) response against telomerase-expressing tumor cells. Directly linked to tumorigenesis, telomerase is expressed in the majority of human cancer cells but is infrequently expressed in normal cells. (NCI Thesaurus)
YOU MAY ALSO LIKE
Human HTC2 gene is located within Xq24-q27.1 and the size of this phenotypic locus is not reported. This gene region has no…
Human HTATIP2 wild-type allele is located in the 11p15.1 and is approximately 20 kb in length. This allele, which encodes oxidoreductase HTATIP2…
This gene is involved in the regulation of apoptosis and induces cell death.
Bipartite DNA binding domain containing a helix-turn and a leucine zipper.
Human colonic adenocarcinoma cells that are able to express differentiation features characteristic of mature intestinal cells. These cells have mainly been used…
hSWI/SNF is an ATP-dependent chromatin-remodeling complex implicated in the regulation of gene expression, cell cycle control, and oncogenesis. The complex facilitates transcriptional…
