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    Human Herpesvirus 1

    Definition 1

    HSV is a nuclear replicating, icosahedral, enveloped DNA virus. The HSV envelope contains at least 8 glycoproteins. The matrix or tegument which contacts both the envelope and the capsid contains at least 15-20 proteins. There are two types of HSV - Type 1 and Type 2. The Type 1 virus causes cold sores. Most people get Type 1 infections during infancy or childhood. The Type 2 virus causes genital sores. Most people get Type 2 infections following sexual contact with an infected person. (NCI Thesaurus)

    Definition 2

    A genus of the family HERPESVIRIDAE, subfamily ALPHAHERPESVIRINAE, consisting of herpes simplex-like viruses. (NLM, Medical Subject Headings)

    Definition 3

    A type of virus that causes herpes infections and has DNA as its genetic material. There are two types of herpes simplex viruses. Infections with type 1 viruses cause cold sores on the lips or nostrils. Infections with type 2 viruses cause sores on the genitals (external and internal sex organs and glands). (NCI Dictionary)

    Definition 4

    Any viral organism that can be assigned to the species Human Herpesvirus 1 within the genus Simplexvirus. (NCI Thesaurus/CDISC)




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