Library / English Dictionary

HYBRIDIZE

Pronunciation (US):

(GB):

 I. (verb) 

Sense 1

Meaning:

Breed animals or plants using parents of different races and varieties

Example:

these species do not interbreed

Synonyms:

cross; crossbreed; hybridise; hybridize; interbreed

Classified under:

Verbs of touching, hitting, tying, digging

Hypernyms (to "hybridize" is one way to...):

breed (cause to procreate (animals))

Troponyms (each of the following is one way to "hybridize"):

backcross (mate a hybrid of the first generation with one of its parents)

Sentence frame:

Somebody ----s something

Derivation:

hybrid ((genetics) an organism that is the offspring of genetically dissimilar parents or stock; especially offspring produced by breeding plants or animals of different varieties or breeds or species)

hybrid (a composite of mixed origin)

hybridization; hybridizing ((genetics) the act of mixing different species or varieties of animals or plants and thus to produce hybrids)

Credits

 Context examples: 

MG 98 is a highly specific inhibitor of translation of the mRNA for human DNA (cytosine-5-)-methyltransferase 1 (DNMT1), hybridizing to the 3' un-translated region of DNMT1 mRNA.

(MG 98, NCI Thesaurus)

The labeled, denatured DNA fragments are applied to a DNA microarray where they can hybridize to their complementary DNA sequence.

(ChIP-On-Chip, NCI Thesaurus)

Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present.

(DNA Probes, NLM, Medical Subject Headings)

Anti-HIF-1alpha LNA antisense oligonucleotide EZN-2968 hybridizes with HIF-1alpha mRNA and blocks t HIF-1 alpha protein expression, which may result in the inhibition of angiogenesis, the inhibition of tumor cell proliferation, and apoptosis.

(Anti-HIF-1alpha LNA Antisense Oligonucleotide EZN-2968, NCI Thesaurus)

Upon administration, EZN-4176 is hybridized and releases the complementary sequences of AR mRNA, thereby blocking translation of the AR protein and inhibiting AR-induced tumor cell growth and promoting tumor cell apoptosis in AR-overexpressing tumor cells.

(Androgen Receptor Antisense Oligonucleotide EZN-4176, NCI Thesaurus)

RNA extracted from a sample was denatured and separated by slab gel electrophoresis, then blotted on to a nitrocellulose or nylon sheet and hybridized with labeled DNA or RNA that is complementary to the desired RNA, whose presence is subsequently indicated by autoradiography or other visualization techniques.

(Northern Blotting, NCI Thesaurus)

"Other work has documented that some songbird species can smell, and prefer their own species' odors, but this is the first example in currently hybridizing species that we know of."

(Scent brings songbirds to the yard, National Science Foundation)

They wondered whether smell might contribute to the reproductive isolation of black-capped and Carolina chickadees in a zone in Pennsylvania where birds are hybridizing.

(Scent brings songbirds to the yard, National Science Foundation)