Library / English Dictionary

    HYDROXY

    Pronunciation (US): Play  (GB): Play

     I. (adjective) 

    Sense 1

    Meaning:

    Being or containing a hydroxyl groupplay

    Classified under:

    Relational adjectives (pertainyms)

    Pertainym:

    hydroxyl (the monovalent group -OH in such compounds as bases and some acids and alcohols)

    Credits

     Context examples: 

    In the body lovastatin is hydrolysed to its beta-hydroxy acid active form.

    (Lovastatin Acid, NCI Thesaurus)

    It is a sodium or calcium salt of [4-(alpha-(4-diethylaminophenyl)-5-hydroxy- 2,4-disulfophenyl-methylidene)-2,5-cyclohexadien-1-ylidene] diethylammonium hydroxide inner salt.

    (Patent Blue V Dye, NCI Thesaurus)

    SR-45023A binds to hydroxyapatite crystals in the bone matrix where it inhibits enzymatic activity of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, which is required for the formation of mevalonate, the precursor of cholesterol.

    (Apomine, NCI Thesaurus)

    Colestolone targets sterol regulatory element binding protein (SREBP) which reduces the transcription of the 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) gene, the rate-limiting enzyme in the sterol pathway.

    (Colestolone, NCI Thesaurus)

    An organic salt containing a one to one ratio of methenamine, a heterocyclic organic compound, and mandelic acid, an aromatic alpha hydroxy acid, used in the treatment of urinary tract infections.

    (Methenamine Mandelate, NCI Thesaurus)

    A calcium-free, iron and magnesium hydroxy carbonate and inorganic phosphate binder with phosphate lowering activity.

    (Fermagate, NCI Thesaurus)

    In addition, this agent is capable of inhibiting rapid desensitization of the ionotropic alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptors, thereby potentiating glutamate responses which may induce seizures activity.

    (Cyclothiazide, NCI Thesaurus)

    Fluvastatin competitively inhibits hepatic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis.

    (Fluvastatin, NCI Thesaurus)

    Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring (IUPAC).

    (Lactone Compound, NCI Thesaurus)

    Fluvastatin competitively inhibits hepatic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis.

    (Fluvastatin Sodium, NCI Thesaurus)


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