| Health / Medical Topics |
ICOS wt Allele
Human ICOS wild-type allele is located in the vicinity of 2q33 and is approximately 25 kb in length. This allele, which encodes inducible T-cell costimulator protein, plays a role in the modulation of T-cell mediated immunity. Mutation of the gene is associated with common variable immunodeficiency type 1. (NCI Thesaurus)
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This gene is involved in the immune response.
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