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Idarubicin
Pronunciation
Definition 1
An anticancer drug that is a type of antitumor antibiotic. Also called 4-demethoxydaunorubicin. (NCI Dictionary)
Definition 2
A semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes with the activity of topoisomerase II, thereby inhibiting DNA replication, RNA transcription and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds. (NCI Thesaurus)
Definition 3
An anticancer drug that belongs to the family of drugs called antitumor antibiotics. (NCI Dictionary)
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