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Idoxuridine
Pronunciation
Definition 1
A drug that reduces the risk of cancer cell growth by interfering with the cells' DNA. (NCI Dictionary)
Definition 2
An iodinated analog of deoxyuridine originally developed as a chemotherapeutic agent, but more commonly used as a treatment for conditions of herpes virus infection. Idoxuridine inhibits thymidylate phosphorylase and viral DNA polymerases. It is converted in vivo to its mono-, di-, and triphosphate forms and is incorporated into DNA by competition with thymidine. Once incorporated into DNA it creates a faulty template and disrupts viral replication. (NCI Thesaurus)
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