| Health / Medical Topics |
IDS wt Allele
Human IDS wild-type allele is located in the vicinity of Xq28 and is approximately 27 kb in length. This allele, which encodes iduronate 2-sulfatase protein, plays a role in the mediation of proteoglycan turnover. Mutations in the gene that result in enzymatic deficiency of the gene product are associated with Mucopolysaccharidosis Type II (Hunter Syndrome). (NCI Thesaurus)
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This gene is involved in proteoglycan metabolism.
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