Health / Medical Topics |
IFNAR2 wt Allele
Human IFNAR2 wild-type allele is located in the vicinity of 21q22.11 and is approximately 35 kb in length. This allele, which encodes interferon-alpha/beta receptor beta chain protein, plays a role in tyrosine-kinase signal transduction and the mediation of innate immune responses to viral infection. (NCI Thesaurus)
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This gene is involved in tyrosine-kinase signal transduction that elicits signaling events in the Jak/Stat and IRS pathways.
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