IKZF1 wt Allele

Human IKZF1 wild-type allele is located within 7p13-p11.1 and is approximately 123 kb in length. This allele, which encodes DNA-binding protein Ikaros, plays a role in transcriptional enhancement. Truncated and mutated forms of the gene can be a factor in acute lymphoblastic leukemia. A translocation t(3;7)(q27;p12) that fuses the gene to the BCL6 gene is implicated in diffuse large B-cell lymphomas. (NCI Thesaurus)

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IKZF1 Gene

This gene is involved in B-cell and T-cell maturation.

IKBKG wt Allele

Human IKBKG wild-type allele is located in the vicinity of Xq28 and is approximately 25 kb in length. This allele, which encodes…

IKBKG Gene

This gene plays a role in the regulation of signal transduction.

IKBKB wt Allele

Human IKBKB wild-type allele is located in the vicinity of 8p11.2 and is approximately 61 kb in length. This allele, which encodes…

IKBKB Gene

This gene is involved in protein phosphorylation.

IKBIP wt Allele

Human IKBIP wild-type allele is located in the vicinity of 12q23.1 and is approximately 31 kb in length. This allele, which encodes…