IKZF3 wt Allele

Human IKZF3 wild-type allele is located in the vicinity of 17q21 and is approximately 99 kb in length. This allele, which encodes zinc finger protein Aiolos, is involved in the modulation of both lymphocyte development and transcription. Genetic variation may be associated with both the occurrence and relapse of acute lymphoblastic leukemia. (NCI Thesaurus)

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IKZF3 Gene

This gene plays a role in both transcription in hematopoietic cells and lymphocyte development.

IKZF2 wt Allele

Human IKZF2 wild-type allele is located in the vicinity of 2q34 and is approximately 152 kb in length. This allele, which encodes…

IKZF2 Gene

This gene is involved in both transcription and lymphocyte development.

IKZF1/BCL6 Fusion Gene

A fusion gene that results from a chromosomal translocation t(3;7)(q27;p12) which fuses the promoter of the IKZF1 gene near the 5' end…

IKZF1 wt Allele

Human IKZF1 wild-type allele is located within 7p13-p11.1 and is approximately 123 kb in length. This allele, which encodes DNA-binding protein Ikaros,…

IKZF1 Gene

This gene is involved in B-cell and T-cell maturation.