IL12RB2 wt Allele

Human IL12RB2 wild-type allele is located within 1p31.3-p31.2 and is approximately 90 kb in length. This allele, which encodes interleukin-12 receptor beta-2 chain protein, plays a role in the proliferation of both T cells and natural killer cells. It is also involved in Th1 cell differentiation. Up-regulation of the IL12RB2 gene is associated with certain infectious diseases such as Crohn's disease and leprosy. (NCI Thesaurus)

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IL12RB2 Gene

This gene is involved in cellular signaling. It is also involved in the immune response and host defense in Leprosy.

IL12RB1 wt Allele

Human IL12RB1 wild-type allele is located in the vicinity of 19p13.1 and is approximately 74 kb in length. This allele, which encodes…

IL12RB1 Gene

This gene plays a role in cellular signaling and is involved in immunity/defense.

IL12B wt Allele

Human IL12B wild-type allele is located within 5q31.1-q33.1 and is approximately 16 kb in length. This allele, which encodes interleukin-12 beta chain…

IL12B Gene

This gene is involved in immunity/defense via the stimulation of both T cells and natural killer cells. It also plays a role…

IL12A wt Allele

Human IL12A wild-type allele is located within 3p12-q13.2 and is approximately 7 kb in length. This allele, which encodes interleukin-12 alpha chain…