IL2 Signaling Pathway

Interleukin 2 (IL-2) is a potent cytokine that can lead to cellular activation and proliferation. IL-2 receptors are found on activated B-cells, LPS treated monocytes, and many T-cells. The receptor is formed from three chains, alpha (CD25), beta (CD122), and gamma (CD132). Primary signaling is through the JAK/Stat pathway and MAPKs. (NCI Thesaurus/BIOCARTA)

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IL2 Receptor Beta

IL2 receptor beta (551 aa, 61 kD) is a cell communication process protein that is encoded by the human IL2RB gene and…

IL2 Gene

This gene is involved in growth and lymphokine regulation.

IL1RN wt Allele

Human IL1RN wild-type allele is located in the vicinity of 2q14.2 and is approximately 27 kb in length. This allele, which encodes…

IL1RN Gene

This gene is involved in the inhibition of signaling.

IL1RL1 wt Allele

Human IL1RL1 wild-type allele is located in the vicinity of 2q12 and is approximately 41 kb in length. This allele, which encodes…

IL1RL1 Gene

This gene plays a role in interleukin binding and receptor signaling.