IL2 wt Allele

Human IL2 wild-type allele is located within 4q26-q27 and is approximately 5 kb in length. This allele, which encodes interleukin-2 protein, plays a role in the proliferation of T and B lymphocytes. IL2 also has a putative role in immune responses to antigenic stimuli. Further, the expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. (NCI Thesaurus)

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This gene is involved in growth and lymphokine regulation.

IL1RN wt Allele

Human IL1RN wild-type allele is located in the vicinity of 2q14.2 and is approximately 27 kb in length. This allele, which encodes…

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This gene is involved in the inhibition of signaling.

IL1RL1 wt Allele

Human IL1RL1 wild-type allele is located in the vicinity of 2q12 and is approximately 41 kb in length. This allele, which encodes…