IL4 Signaling Pathway

Interleukin 4 (IL-4) is a cytokine that can lead to development of Th2 cells. The 140 kD IL-4 Receptor (CD124) is found on many cell types, even those of non-hematopoietic origin. The receptor is formed from two chains: IL-4R-alpha and the IL-2R gamma chain (CD132). Primary signaling is through the JAK/Stat6 pathway and MAPKs. (NCI Thesaurus/BIOCARTA)

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IL4 Gene

This gene is involved in the regulation of the proliferation and differentiation of B-cells.

IL3RA wt Allele

Human IL3RA wild-type allele is located in the vicinity of Yp22.33 and is approximately 46 kb in length. This allele, which encodes…

IL3RA Gene

This gene is involved in signal transduction and several diverse biological processes.

IL33 wt Allele

Human IL33 wild-type allele is located in the vicinity of 9p24.1 and is approximately 42 kb in length. This allele, which encodes…

IL33 Gene

This gene plays a role in cytokine signaling.

IL3 wt Allele

Human IL3 wild-type allele is located in the vicinity of 5q31.1 and is approximately 3 kb in length. This allele, which encodes…