IL4R wt Allele

Human IL4R wild-type allele is located within 16p11.2-12.1 and is approximately 35 kb in length. This allele, which encodes interleukin-4 receptor alpha chain protein, plays a role in Th2 cell differentiation, immunoglobulin E (IgE) production and cellular proliferation regulation. Allelic variants are associated with atopy. This condition can be typified as allergic rhinitis, sinusitus, asthma, or eczema. (NCI Thesaurus)

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IL4R Gene

This gene plays a prominent role in immunoglobulin E production and cellular signal transduction.

IL4-Pseudomonas Exotoxin Fusion Protein PRX321

A fusion protein consisting of the cytokine interleukin-4 (IL-4) linked to a truncated form of Pseudomonas exotoxin with potential antineoplastic activity. Upon…

IL4 wt Allele

Human IL4 wild-type allele is located in the vicinity of 5q31.1 and is approximately 9 kb in length. This allele, which encodes…

IL4 Signaling Pathway

Interleukin 4 (IL-4) is a cytokine that can lead to development of Th2 cells. The 140 kD IL-4 Receptor (CD124) is found…

IL4 Gene

This gene is involved in the regulation of the proliferation and differentiation of B-cells.

IL3RA wt Allele

Human IL3RA wild-type allele is located in the vicinity of Yp22.33 and is approximately 46 kb in length. This allele, which encodes…