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IL-2 Plasmid DNA/Lipid Complex
Definition 1
An immunotherapeutic agent consisting of a plasmid DNA encoding human Interleukin-2 (IL-2) complexed with a cationic lipid, 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE), in a 5:1 ratio. Due to the lipophilic nature of this cation liposome complex, this gene transfer system may improve the efficiency of introducing the IL-2 gene into the cells, thereby increasing the production of IL-2 and inducing an immune response. (NCI Thesaurus)
Definition 2
An agent that delivers the gene for interleukin-2 (IL-2) into cells to increase production of IL-2 by the cells. (NCI Dictionary)
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