Imatinib

An antineoplastic agent that inhibits the Bcr-Abl fusion protein tyrosine kinase, an abnormal enzyme produced by chronic myeloid leukemia cells that contain the Philadelphia chromosome. Imatinib also inhibits the receptor tyrosine kinases for platelet-derived growth factor (PDGF) and stem cell factor (SCF)/c-kit; the SCF/c-kit receptor tyrosine kinase is activated in gastrointestinal stromal tumor (GIST). This agent inhibits proliferation and induces apoptosis in cells that overexpress these oncoproteins. (NCI Thesaurus)

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A type of test that makes pictures of areas inside the body. Some examples of imaging tests are CT scans and…

Imaging Technology

Any of a number of technologies that permits the visualization and acquisition of images into a physical or electronic record.

Imaging Technique

Any technology or method that aids in the visualization of any biological process, cell, tissue or organ for use in screening, diagnosis,…

Imaging System

A group of instruments designed to view, capture, process and display an image.

Imaging Signal

The measured value of a response in a recorded image produced by the intensity, abundance, or concentration of source materials.

Imaging Region of Interest

A specific area of interest defined by a sequence of image overlays or a sequence of contours described as a single point…