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IMMUNE RESPONSE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A bodily defense reaction that recognizes an invading substance (an antigen: such as a virus or fungus or bacteria or transplanted organ) and produces antibodies specific against that antigen
Synonyms:
immune reaction; immune response; immunologic response
Classified under:
Nouns denoting acts or actions
Hypernyms ("immune response" is a kind of...):
reaction; response (a bodily process occurring due to the effect of some antecedent stimulus or agent)
Meronyms (parts of "immune response"):
complement (one of a series of enzymes in the blood serum that are part of the immune response)
Domain category:
bacteria; bacterium ((microbiology) single-celled or noncellular spherical or spiral or rod-shaped organisms lacking chlorophyll that reproduce by fission; important as pathogens and for biochemical properties; taxonomy is difficult; often considered to be plants)
fungus (an organism of the kingdom Fungi lacking chlorophyll and feeding on organic matter; ranging from unicellular or multicellular organisms to spore-bearing syncytia)
Hyponyms (each of the following is a kind of "immune response"):
anamnestic reaction; anamnestic response (renewed rapid production of an antibody on the second (or subsequent) encounter with the same antigen)
humoral immune response (an immune response (chiefly against bacterial invasion) that is mediated by B cells)
cell-mediated immune response (an immune response (chiefly against viral or fungal invasions or transplanted tissue) that involves T cells)
complement fixation (an immune response in which an antigen-antibody combination inactivates a complement (so it is unavailable to participate in a second antigen-antibody combination))
Context examples:
It also lowers the body’s immune response.
(Afinitor, NCI Dictionary)
Upon administration, the AIM2(-1)/HT001(-1)/TAF1B(-1) FSP vaccine may induce an immune response against microsatellite instability (MSI) colorectal cancer-associated antigens.
(AIM2(-1)/HT001(-1)/TAF1B(-1) Frameshift Peptide Vaccine, NCI Thesaurus)
Vaccines using pieces of the Melanoma Antigen Recognized by T cells 1 are being studied for their ability to boost the immune response to cancer cells in patients with melanoma.
(Melanoma Antigen Recognized by T cells 1, NCI Dictionary)
Mesangial cells serve as structural supports, may regulate blood flow, are phagocytic and may act as accessory cells, presenting antigen in immune responses.
(Mesangial Cell, NCI Thesaurus)
They are found only in lymphoid organs and at sites of immune responses and normally do not circulate in the blood or lymph.
(Murine Plasma Cells, NLM, Medical Subject Headings)
Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B-cells during an immune response.
(Murine Follicular Dendritic Cells, NLM, Medical Subject Headings)
They also stimulate other cellular immune responses.
(Murine T-Lymphocytes, Suppressor-Inducer, NLM, Medical Subject Headings)
Upon administration, MVA EBNA1/LMP2 vaccine may elicit a cytotoxic T-cell immune response against cancer cells expressing EBNA1 and LMP2.
(MVA-EBNA1/LMP2 Vaccine, NCI Thesaurus)
Upon administration, MVA-PSA-PAP prostate cancer vaccine expresses PSA and PAP peptides, which may elicit humoral and cellular immune responses against prostate cancer cells expressing PSA and PAP.
(MVA-PSA/PAP Prostate Cancer Vaccine, NCI Thesaurus)
MUC1 antigen is linked with KLH, an immunostimulant and a hapten carrier, in order to enhance immune recognition; the co-administration of saponin-derived QS21 potentially amplifies the total immune response to the MUC1 antigen.
(MUC1-KLH Vaccine/QS21, NCI Thesaurus)
