| Health / Medical Topics |
Immunoglobulin Binding Protein 1
Ubiquitously expressed (highest in heart, skeletal muscle, and pancreas) by human IGBP1 Gene, 339-aa 39-kDa Immunoglobulin Binding Protein 1 is likely involved in IgM/B-Cell Receptor signal transduction. Similar to mouse Igbp1 and yeast TAP42, IGBP1 contains potential N-glycosylation sites, myristylation sites, multiple potential PKC and casein kinase II phosphorylation sites, and an SH3-binding sequence-related stretch. IGBP1 associates with and likely regulates the activity of Ser/Thr phosphatase PP2A-Alpha and PP2A-Beta catalytic subunits. IGBP1 also associates with PP4 and PP6. (NCI Thesaurus)
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