| Health / Medical Topics |
Immunoglobulin Hinge Region
A region of relative flexibility between the variable and constant regions of an antibody molecule. (NCI Thesaurus)
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This region represents the germline organization of the immunoglobulin heavy chain locus. The locus includes V (variable), J (joining), diversity (D), and…
A change in the nucleotide sequence of the variable region of the immunoglobulin heavy chain locus.
A disorder that affects the production of complete immunoglobulins. Deletions in the heavy chain genes on chromosome 14 disrupt the synthesis and…
A protein complex that consists of two heavy chains (gamma, alpha, delta, epsilon or mu). The larger of the two immunoglobulin chain…
Any process of gene rearrangement that creates a novel junction among the immunoglobuling-coding variable, diversity, joining or constant segments. This process involves…
The determination of the amount of immunoglobulin G present in a sample.
