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Immunoglobulin Joining Region
The portion of the light and heavy chains of immunoglobulin molecules where the variable and constant regions meet. (NCI Thesaurus)
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This region represents the germline organization of the immunoglobulin heavy chain locus. The locus includes V (variable), J (joining), diversity (D), and…
A change in the nucleotide sequence of the variable region of the immunoglobulin heavy chain locus.
A disorder that affects the production of complete immunoglobulins. Deletions in the heavy chain genes on chromosome 14 disrupt the synthesis and…
A protein complex that consists of two heavy chains (gamma, alpha, delta, epsilon or mu). The larger of the two immunoglobulin chain…
