Health / Medical Topics |
Immunoglobulin Light Chain
A protein complex that consists of two light chains (kappa and lambda). The light chain molecules are of the same structure and composition, consisting of constant, variable, and hypervariable regions. (NCI Thesaurus)
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This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant)…
This region represents the germline organization of the kappa light chain locus. The locus includes V (variable), J (joining), and C (constant)…
The portion of the light and heavy chains of immunoglobulin molecules where the variable and constant regions meet.
Within the variable domain of an antibody molecule are three regions called hypervariable regions, areas of high sequence diversity. These regions…
A region of relative flexibility between the variable and constant regions of an antibody molecule.
This region represents the germline organization of the immunoglobulin heavy chain locus. The locus includes V (variable), J (joining), diversity (D), and…